Plastic Surgeon San Francisco - Pacific Heights Plastic Surgery (2024)

We’re very excited to release our October weight loss data from our weight management program that includes semaglutide (the active ingredient found in Ozempic and Wegovy) and tirzepatide (the active ingredient in Mounjaro). The medications we offer come from a compounding pharmacy which by law, must be a duplicate of these name brand active ingredients while Ozempic, Wegovy and Mounjaro are on the FDA shortage list.

Weight loss on semaglutide after 8 months

This first graph shows the effects of semaglutie on our patients over the last 8 months. As you can see, the average weight loss is 7.59 pounds in the first month, 12.86 pounds over the first two months, 18.23 pounds over the first three months, 23.49 pounds over the first four months, 27.27 pounds over the first five months, 32.83 pounds over the first six months, 38.49 pounds over the first seven months and then 40.92 pounds over the first eight months. At eight months, that weight loss equates to 27% of the patient’s body weight! According to the FDA submission for Wegovy approval (the weight loss medication produced by NovoNordisk that contains the active ingredient semaglutide), the average weight loss over 1 year and 4 months was 15.1%! We’re not saying our semaglutide is better than their semaglutide, we’re just saying that our compounded version of semaglutide is the real deal!

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When semaglutide patients switch to tirzepatide

In the graph below, you can see that patients who switched from semaglutide to tirzepatide, either because of greater side effects on semaglutide or because they felt they hit a plateau on semaglutide, they continued to lose weight on tirzepatide. Not necessarily at a faster rate but the graph shows that weight loss of both medications follows the same downward trend that we want to see when it comes to weight loss.

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Weight loss on tirzepatide after 4 months

So is tirzepatide better than semaglutide when it comes to weight loss? As described above, with semaglutide, the average weight loss is 7.59 pounds in the first month, 12.86 pounds over the first two months, 18.23 pounds over the first three months, 23.49 pounds over the first four months.

For tirzepatide, the average weight loss is 8.31 pounds in the first month, (not even a pound greater than semaglutide), 15.73 pounds over the first two months (almost three pounds more than semaglutide), 19.34 pounds over the first three months (a pound greater than semaglutide) and 26.40 pounds over the first four months (three pounds more than semaglutide).

Semaglutide is $500 per month in our practice and tirzepatide is $600 per month. You may not think that difference in weight loss is enough to spend $100 more on tirzepatide. But as the graphs below show, the side effects occur less often in patients who’ve switched from semaglutide to tirzepatide. Which will you choose?!