Overview of the Digestive System - Digestive Disorders - MSD Manual Consumer Version (2024)

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Overview of the Digestive System Throat and Esophagus Stomach Small Intestine Pancreas Large Intestine Rectum and Anus Effects of Aging on the Digestive System

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Michael Bartel

, MD, PhD, Fox Chase Cancer Center, Temple University

Reviewed/Revised Oct 2022 | Modified Feb 2023

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Overview of the Digestive System

Overview of the Digestive System - Digestive Disorders - MSD Manual Consumer Version (4)

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The digestive system, which extends from the mouth to the anus, is responsible for receiving food, breaking it down into nutrients (a process called digestion), absorbing the nutrients into the bloodstream, and eliminating the indigestible parts of food from the body. The digestive tract consists of the

  • Mouth Biology of the Mouth The mouth is the entrance to both the digestive and the respiratory systems. The inside of the mouth is lined with mucous membranes. When healthy, the lining of the mouth (oral mucosa) ranges... read more

  • Throat and esophagus Throat and Esophagus The throat (pharynx) lies behind and below the mouth. When food and fluids leave the mouth, they pass through the throat. Swallowing of food and fluids begins voluntarily and continues automatically... read more

  • Stomach Stomach The stomach is a large, bean-shaped, hollow muscular organ consisting of four regions: Cardia Fundus Body Antrum read more

  • Small intestine Small Intestine The duodenum is the first segment of the small intestine, and the stomach releases food into it. Food enters the duodenum through the pyloric sphincter in amounts that the small intestine can... read more

  • Large intestine Large Intestine The large intestine consists of the Cecum and ascending (right) colon Transverse colon Descending (left) colon Sigmoid colon (which is connected to the rectum) read more

  • Rectum and anus Rectum and Anus The rectum is a chamber that begins at the end of the large intestine, immediately following the sigmoid colon, and ends at the anus ( see also Overview of the Anus and Rectum). Ordinarily,... read more

The digestive system also includes organs that lie outside the digestive tract:

  • The pancreas Pancreas The pancreas is an organ that contains two types of glandular tissue: Pancreatic acini Islets of Langerhans (See also Overview of the Digestive System.) The acini produce digestive enzymes.... read more

  • The liver Liver The wedge-shaped liver is the largest—and, in some ways, the most complex—organ in the body. It serves as the body's chemical factory, performing many vital functions, from regulating the levels... read more

  • The gallbladder Gallbladder and Biliary Tract The gallbladder is a small, pear-shaped, muscular storage sac that holds bile and is interconnected to the liver by ducts known as the biliary tract. (See also Overview of the Liver and Gallbladder... read more

  • The salivary glands Biology of the Mouth The mouth is the entrance to both the digestive and the respiratory systems. The inside of the mouth is lined with mucous membranes. When healthy, the lining of the mouth (oral mucosa) ranges... read more

The digestive system is sometimes called the gastrointestinal system, but neither name fully describes the system’s functions or components. The organs of the digestive system also produce blood clotting factors and hormones unrelated to digestion, help remove toxic substances from the blood, and chemically alter (metabolize) drugs.

The abdominal cavity is the space that holds most of the digestive organs. It is bordered by the abdominal wall (composed of layers of skin, fat, muscle, and connective tissue) in front, the spinal column in back, the diaphragm above, and the pelvic organs below. It is lined by a membrane called the peritoneum. The peritoneum lines most of the outer surfaces of the digestive organs.

Experts have recognized a powerful connection between the digestive system and the brain. For example, psychologic factors greatly influence contractions of the intestine, secretion of digestive enzymes, and other functions of the digestive system. Even susceptibility to infection, which leads to various digestive system disorders, is strongly influenced by the brain. In turn, the digestive system influences the brain. For example, long-standing or recurring diseases such as irritable bowel syndrome Irritable Bowel Syndrome (IBS) Irritable bowel syndrome is a disorder of the digestive tract that causes recurring abdominal pain and constipation or diarrhea. Symptoms vary but often include lower abdominal pain, bloating... read more , ulcerative colitis Ulcerative Colitis Ulcerative colitis is a chronic inflammatory bowel disease in which the large intestine (colon) becomes inflamed and ulcerated (pitted or eroded), leading to flare-ups (bouts or attacks) of... read more , and other painful diseases affect emotions, behaviors, and daily functioning. This two-way association has been called the brain-gut axis.

Aging may also affect how the digestive system functions (see Effects of Aging on the Digestive System Effects of Aging on the Digestive System Because the digestive system has a lot of reserve built into it, aging has less effect on its function than it does on the function of other organ systems. Nonetheless, aging is a factor in... read more ).

The Digestive System

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FAQs

What is the general overview of the digestive system? ›

The digestive system breaks down food and absorbs nutrients for energy and growth. It is a long tube starting from your mouth, going all the way to your anus. Common digestive health conditions are gastro-oesophageal reflux disease (GORD), diverticulitis, stomach ulcers, and haemorrhoids.

What are the digestive diseases summary? ›

A digestive disease is any health problem that occurs in the digestive tract. Conditions may range from mild to serious. Some common problems include heartburn, cancer, irritable bowel syndrome, and lactose intolerance.

What are the disorders of the digestive system? ›

Common digestive disorders include gastroesophageal reflux disease, cancer, irritable bowel syndrome, lactose intolerance and hiatal hernia. The most common symptoms of digestive disorders include bleeding, bloating, constipation, diarrhea, heartburn, pain, nausea and vomiting.

What is the GI system overview? ›

The GI tract consists of the oral cavity, pharynx, esophagus, stomach, small intestine, large intestine, and anal canal. The accessory organs include the teeth, tongue, and glandular organs such as salivary glands, liver, gallbladder, and pancreas.

What are the parts of the digestive system summary? ›

The GI tract is a series of hollow organs joined in a long, twisting tube from the mouth to the anus. The hollow organs that make up the GI tract are the mouth, esophagus, stomach, small intestine, large intestine, and anus. The liver, pancreas, and gallbladder are the solid organs of the digestive system.

What are gastrointestinal disorders summary? ›

What are gastrointestinal diseases? Gastrointestinal diseases affect your gastrointestinal (GI) tract, from mouth to anus. There are two types: functional and structural. Some examples include colitis, food poisoning, lactose intolerance and diarrhea.

How to get rid of digestion problems? ›

Here's a tummy friendly diet to aim for.
  1. Fill up on fibre to prevent constipation. ...
  2. Drink plenty of fluids to aid digestion. ...
  3. Cut down on fat for a healthy gut. ...
  4. Go easy on spice to avoid tummy troubles. ...
  5. Beware gut symptom triggers. ...
  6. Choose the right drinks to ease digestion. ...
  7. Probiotics.

How do you treat a digestive disorder? ›

Diet and lifestyle changes can make a big difference:
  • Cut back on fatty foods.
  • Avoid fizzy drinks.
  • Eat and drink slowly.
  • Quit smoking.
  • Don't chew gum.
  • Exercise more.
  • Avoid foods that cause gas.
  • Avoid sweeteners that cause gas such as fructose and sorbitol.
Mar 24, 2023

What are the symptoms of a serious stomach problem? ›

However, symptoms such as gas, bloating, pain, vomiting, diarrhea, and constipation can also be due to conditions of the abdominal wall, blood vessels, urinary tract, reproductive organs, or even chest organs. Generalized stomach problems may be due to diet, infection, or inflammation.

How to diagnose stomach problems? ›

Standard imaging tests for gastric conditions include upper gastrointestinal series (UGI), ultrasounds, MRIs, CT scans and X-rays. For an even clearer picture of the gastrointestinal tract, a barium swallow or barium enema may be used in conjunction with an X-ray.

What is wrong with my gut? ›

Frequent discomfort, gas, bloating, constipation, diarrhea, and heartburn could be signs that your gut is having a hard time processing food and eliminating waste. You feel tired more often than not. People with chronic fatigue may have imbalances in the gut.

What are the four main functions of the digestive system? ›

What Is the Digestive System? Motility, digestion, absorption and secretion are the four vital functions of the digestive system. The digestive system breaks down the foods we eat into energy our bodies can use.

What are the symptoms of gastrointestinal disease? ›

Signs and Symptoms
  • Change in bowel habits.
  • Unexplained weight loss.
  • Rectal bleeding or bloody stools.
  • Weakness or fatigue.
  • Abdominal pain or cramping.
  • Incomplete bowel movements.

What does the digestive system do? ›

The digestive system converts the foods we eat into their simplest forms, like glucose (sugars), amino acids (that make up protein) or fatty acids (that make up fats). The broken-down food is then absorbed into the bloodstream from the small intestine and the nutrients are carried to each cell in the body.

What is the general information about the human digestive system? ›

The digestive system converts the foods we eat into their simplest forms, like glucose (sugars), amino acids (that make up protein) or fatty acids (that make up fats). The broken-down food is then absorbed into the bloodstream from the small intestine and the nutrients are carried to each cell in the body.

What is digestion short answer? ›

Digestion is the process of mechanically and enzymatically breaking down food into substances for absorption into the bloodstream. The food contains three macronutrients that require digestion before they can be absorbed: fats, carbohydrates, and proteins.

What is the process of digestion step by step? ›

The digestive processes are ingestion, propulsion, mechanical digestion, chemical digestion, absorption, and defecation. Some chemical digestion occurs in the mouth. Some absorption can occur in the mouth and stomach, for example, alcohol and aspirin.

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